Then, if needed, she will order tests to get pictures of your kidneys and urinary tract. What is the most important information I should know about tolterodine Detrol? First, she will get a medical history and examine you. The use of Demerol Injection in patients with acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment is contraindicated. The onset of symptoms generally occurs within several hours to a few days of concomitant use, but may occur later than that. Discontinue Demerol Injection if serotonin syndrome is suspected.
Opioids are sought by drug abusers and people with addiction disorders and are subject to criminal diversion. Consider these risks when prescribing or dispensing Demerol Injection. Strategies to reduce these risks include prescribing the drug in the smallest appropriate quantity. To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative such as a stimulant-type with stool softener. Methylprednisolone can make you more likely to get infections or may worsen any current infections. Therefore, well to prevent the spread of infection.
Reserve concomitant prescribing of Demerol Injection and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Demerol Injection should not be used for treatment of chronic pain. If the level of pain increases after dosage stabilization, attempt to identify the source of increased pain before increasing the Demerol Injection dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between management of pain and opioid-related adverse reactions.
These help to strengthen the pelvic floor after childbirth. They also help prevent stress incontinence. Best of all, you can do Kegels anytime, anywhere. The safety and efficacy of Demerol Injection in patients less than 18 years of age have not been established. Meperidine produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. What happens if I overdose Detrol LA? Drug-seeking" behavior is very common in persons with substance use disorders. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing, or referral, repeated "loss" of prescriptions, tampering with prescriptions, and reluctance to provide prior medical records or contact information for other treating health care providers. "Doctor shopping" visiting multiple prescribers to obtain additional prescriptions is common among drug abusers and people suffering from untreated addiction. Preoccupation with achieving adequate pain relief can be appropriate behavior in a patient with poor pain control.
What is tolterodine Detrol? Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Meperidine is metabolized through biotransformation. In vitro data show meperidine is metabolized to normeperidine in liver mainly by CYP3A4 and CYP2B6. See "What Are Side Effects Associated with Using Tolterodine? Talk to your doctor or about lifestyle changes that might benefit you. Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. Monitor for signs of opioid withdrawal. The concomitant use of Demerol Injection and CYP3A4 or CYP2B6 inhibitors can increase the plasma concentration of meperidine, resulting in increased or prolonged opioid effects. Taking flecainide with other agents that can affect your heart rhythm may increase your risk of an irregular heartbeat, which may be life-threatening. Pfizer also has programs that provide eligible patients with insurance, support assistance, and medicines at a savings. Contact Pfizer RxPathways for details 844-989-7284.
First, you complete a chart of the times you pee and the times you leak. You observe patterns and then plan to empty your bladder before an accident would happen. You can also "retrain" your bladder, gradually increasing the time between bathroom visits. Kegel exercises are also helpful. Due to additive pharmacologic effect, the concomitant use of benzodiazepines or other CNS depressants, including alcohol, can increase the risk of hypotension respiratory depression, profound sedation, coma, and death. It is not known whether tolterodine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Think about stirring up your favorite drink from a powder mix. Elderly patients aged 65 years or older may have increased sensitivity to meperidine. In general, use caution when selecting a dosage for an elderly patient, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. kenalog
Older adults may be more sensitive to the side effects of this drug, especially QT prolongation see above drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. In case of overdose, priorities are the reestablishment of a patent and protected airway and institution of assisted or controlled ventilation, if needed. Employ other supportive measures including oxygen and vasopressors in the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require advanced life-support techniques. Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, Philippides GJ, Roden DM, Zareba W. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Medications, electrical stimulation, or surgery. Doctors sometimes prescribe medicines that block the of an overactive bladder. Electrical stimulation of the bladder nerves helps in some cases. Surgery is reserved for severe cases. It aims to increase the amount of urine your bladder can store. Drowsiness and confusion can increase the risk of falling. prescription imuran mg imuran
Demerol Injection may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of Demerol Injection and know how they will react to the medication. Ureteroscopy: This procedure treats stones in the kidneys and ureters. Your doctor uses a thin, flexible scope to find and remove stones. Limit dosage and duration to the minimum required. Use Detrol LA extended-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions. Meperidine hydrochloride is an opioid agonist with multiple actions qualitatively similar to those of morphine; the most prominent of these involve the central nervous system and organs composed of smooth muscle. The principal actions of therapeutic value are analgesia and sedation. The stones can be brown or yellow, and smooth or rough. Americans, most of them women. There are several different types, causes, and treatments. Prescription drug abuse is the intentional non-therapeutic use of a prescription drug, even once, for its rewarding psychological or physiological effects. Because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Tolterodine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. If concomitant use is necessary, consider dosage reduction of Demerol Injection until stable drug effects are achieved. Monitor patients for respiratory depression and sedation at frequent intervals. If concomitant use is necessary, consider increasing the Demerol Injection dosage until stable drug effects are achieved. Monitor for signs of opioid withdrawal. If a CYP3A4 or CYP2B6 inducer is discontinued, consider Demerol Injection dosage reduction and monitor for signs of respiratory depression. Meperidine is contraindicated in patients who are receiving monoamine oxidase MAO inhibitors or those who have recently received such agents. Therapeutic doses of meperidine have occasionally precipitated unpredictable, severe, and occasionally fatal reactions in patients who have received such agents within 14 days. The mechanism of these reactions is unclear, but may be related to a preexisting hyperphenylalaninemia. Some have been characterized by coma, severe respiratory depression, cyanosis, and hypotension, and have resembled the syndrome of acute narcotic overdose. Serotonin syndrome with agitation, hyperthermia, diarrhea, tachycardia, sweating, tremors and impaired consciousness may also occur. In other reactions the predominant manifestations have been hyperexcitability, convulsions, tachycardia, hyperpyrexia, and hypertension.
Meperidine produces peripheral vasodilation which may result in orthostatic hypotension or syncope. Observational studies have demonstrated that concomitant use of opioid analgesics and benzodiazepines increases the risk of drug-related mortality compared to use of opioid analgesics alone. Read the Patient Information Leaflet if available from your before you start taking and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This is a long-acting form of that is used to treat and urinary conditions. If you have any questions about Detrol LA extended-release capsules, please talk with your doctor, pharmacist, or other health care provider. But they are created when your has high levels of certain minerals. Oxybutynin belongs to a class of drugs known as antispasmodics. Prolonged use of opioid analgesics during pregnancy for medical or nonmedical purposes can result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth. Demerol Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia. To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand. Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration. Read the Patient Information Leaflet if available from your pharmacist before you start using tolterodine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. The dosage is based on your medical condition and response to treatment. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling. Cystine stones: This is the least common type. Once you get a cystine stone, there is a chance that you may have one again. You inherit the possibility of getting them from your parents, both of whom would have to have the same type of genetic disorder. ifla.info olmesartan
Take this medication with water. Serious, life-threatening, or fatal respiratory depression may occur with use of Demerol Injection. Tolterodine may cause a condition that affects the heart rhythm QT prolongation. If your kidney stone is small, you may be able to get rid of it when you pee. This may occur within the recommended dosage range. This medication is used to treat an overactive bladder. By relaxing the muscles in the bladder, tolterodine improves your ability to control your urination. It helps to reduce leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom. This medication belongs to the class of drugs known as antispasmodics. The meperidine in Demerol Injection may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis, for worsening symptoms. Blunt cannulas should not be recapped, purposely bent or broken by hand. While serious, life-threatening, or fatal respiratory depression can occur at any time during the use of Demerol Injection, the risk is greatest during the initiation of therapy or following a dosage increase. Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy with and following dosage increases of Demerol Injection. Concomitant use of Demerol Injection with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could decrease meperidine plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to meperidine. It repositions the urethra to help reduce leakage. phenazopyridine generic dollar general
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Most people with not feel sick. While many dieters swear by high-, eating large amounts of can also cause a stone to form. In severe overdose, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. Candesartan belongs to a class of drugs called angiotensin receptor blockers ARBs. It works by relaxing vessels so can flow more easily. Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. Respiratory depression, if not immediately recognized and treated, may lead to respiratory arrest and death. Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. Many drugs besides tolterodine may affect the heart rhythm QT prolongation including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics such as erythromycin among others. Advise both patients and caregivers about the risks of respiratory depression and sedation when Demerol Injection is used with benzodiazepines or other CNS depressants including alcohol and illicit drugs. Advise patients not to drive or operate heavy machinery until the effects of concomitant use of the benzodiazepine or other CNS depressant have been determined. The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down.
Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Struvite stones: Infections, especially in the urinary tract, can cause you to have this kind of stone. Check the Rx Outreach website for the exact price and most current medication list. The major hazards of meperidine, as with other opioid analgesics, are respiratory depression and, to a lesser degree, circulatory depression; respiratory arrest, shock, and cardiac arrest have occurred. If your symptoms do not improve or if they become worse, check with your doctor. Elevated serum levels have been reported to cause central nervous system excitatory effects. Meperidine should therefore be used with caution in patients with hepatic impairment. Titrate the dosage of Demerol Injection slowly in patients with hepatic impairment and monitor closely for signs of central nervous system and respiratory depression. Demerol Injection should be used with caution in patients with atrial flutter and other supraventricular tachycardias because of a possible vagolytic action which may produce a significant increase in the ventricular response rate. buy micronase from canadian pharmacy
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If any of these effects persist or worsen, notify your doctor or promptly. This may interfere with certain laboratory tests such as possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Methylprednisolone may also be used with other in hormone disorders. Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of Demerol Injection in patients with impaired consciousness or coma. What Are Warnings and Precautions for Tolterodine? The half-life of meperidine is 2 to 5 hours, and the half-life of normeperidine is 15 to 30 hours. What other drugs will affect tolterodine Detrol? Instructions for using the Carpuject Syringe are available with the reusable Carpuject Holder. Carpuject Single-use cartridges are to be used ONLY with Carpuject Holders. Prolonged use of Demerol Injection during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Side Effects List Detrol LA side effects by likelihood and severity. Adults: The usual dosage is 50 mg to 100 mg intramuscularly or subcutaneously, 30 to 90 minutes before the beginning of anesthesia. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. There is a relationship between increasing meperidine plasma concentration and increasing frequency of dose-related opioid adverse reactions such as nausea, vomiting, CNS effects, and respiratory depression. generic diovan shipped from usa
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Chronic use of opioids may influence the hypothalamic-pituitary-gonadal axis, leading to androgen deficiency that may manifest as low libido, impotence, erectile dysfunction, amenorrhea, or infertility. Surgery: Another way doctors can get rid of a kidney stone is to cut a small hole in your back and through your kidney in order to remove the stone. If this procedure is done, you could have to stay in the hospital for several days. This means you have any two types of the condition. Many women have both stress and urge incontinence.
It is unknown if this drug passes into milk. Consult your doctor before -feeding. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Caution is advised when using Detrol LA extended-release capsules in CHILDREN; they may be more sensitive to its effects, especially an increased risk for urinary tract infection and behavior or attention problems. Methylprednisolone may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. MAO inhibitors those intended to treat psychiatric disorders and also others, such as linezolid and intravenous methylene blue. If you do not take the same dose each day or if you take this medication every other day, ask your doctor or what you should do if you miss a dose. Oro Valley, AZ 85755. November 17, 2015. Because the duration of opioid reversal is expected to be less than the duration of action of meperidine in Demerol Injection, carefully monitor the patient until spontaneous respiration is reliably re-established. If the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed by the product's prescribing information. Formal reproductive and developmental toxicology studies for meperidine have not been completed. Take this medication by mouth with or without food as directed by your doctor, usually once a day. Swallow the medication whole with a full glass of liquid. Do not crush or chew the medication. Doing so can destroy the long action of the drug and may increase side effects. Do not increase your dose or take this medication more often than directed. Your condition will not improve any faster and your risk of serious side effects may be increased. nootropil
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This may not be a complete list of all interactions that may occur. Ask your health care provider if Detrol LA extended-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. This medication is not recommended for use in children younger than 1 year due to increased risk of side effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Take this by with or without food as directed by your doctor, usually once or twice daily. Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. Woosley RL, Romero KA. www.
Abuse and addiction are separate and distinct from physical dependence and tolerance. Health care providers should be aware that addiction may not be accompanied by concurrent tolerance and symptoms of physical dependence in all addicts. In addition, abuse of opioids can occur in the absence of true addiction. Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. Demerol Injection is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including Demerol Injection, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions. However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression.
If necessary, meperidine may be given intravenously, but the injection should be given very slowly, preferably in the form of a diluted solution. Rapid intravenous injection of narcotic analgesics, including meperidine, increases the incidence of adverse reactions; severe respiratory depression, apnea, hypotension, peripheral circulatory collapse, and cardiac arrest have occurred. Meperidine should not be administered intravenously unless a narcotic antagonist and the facilities for assisted or controlled respiration are immediately available. When meperidine is given parenterally, especially intravenously, the patient should be lying down.